Clinical and Experimental Dermatology | 2021
The predictive diagnostic value of the cytological findings in incontinentia pigmenti: a preliminary report
Abstract
Incontinentia pigmenti (IP) is a genetic disease that develops as a result of X-linked dominant mutation in the nuclear factor κβ kinase subunit gamma gene. This mutation causes random inactivation of one of the X chromosomes and the skin findings IP develop. The skin lesions show different features and these are chronologically separated to 4 stages, which are vesiculobullous (stage 1), verrucous (stage 2), hyperpigmented (stage 3) and hypopigmented (stage 4) stages.1.