Pediatric Allergy and Immunology | 2019
Reply to J. Heinrich
Abstract
We agree with J. Heinrich that randomised controlled trials are the gold standard to infer causality. According to the World Cancer Research Foundation, results from observational studies can however be used to support evidence for causal associations. This is even more valuable that randomized control trials are not always feasible or ethical, as noted by J. Heinrich. Noteworthy, breastfeeding benefits evidence was mostly based on observational studies.