Phototherapy With UVB-NB As A New Adjuvant Therapy For Bullous Pemphigoid: A Pilot Study.

Abstract

Bullous pemphigoid (BP) is an autoimmune blistering skin disease clinically characterized by the development of tense blisters containing serous or hemorrhagic fluid; often patients exhibit a pre-bullous-urticarial eruption and pruritus is a common symptom1 . Since it usually affects the elders, it is often associated with other comorbidities such as diabetes, neurological diseases, internal malignancies and hypertension, and it may be challenging to treat2,3 . The current mainstay of care is topical and/or systemic corticosteroids and immunosuppressants that in the long-term may result in significant morbidity and mortality4 .