IL28B rs12979860 T allele protects against CMV disease in liver transplant recipients in the post‐prophylaxis and late period

Abstract

Cytomegalovirus (CMV) disease represents a serious complication in liver transplant (OLT) recipients. CMV prophylaxis reduces incidence of CMV disease in the early post‐transplant period (on‐prophylaxis disease, OPD) but may postpone its manifestation after the completion of prophylaxis. Post‐prophylaxis disease (PPD) incidence after prophylaxis cessation may be modified by genetic factors.