Simulation platform of large volumetric photoacoustic microscopy based on k-space pseudospectral method

Abstract

We developed a Bessel-beam photoacoustic microscopical simulation platform by using the k-Wave: MATLAB toolbox. The simulation platform uses the ring slit method to generate Bessel beam. By controlling the inner and outer radius of the ring slit, the depth-of-field (DoF) of Bessel beam can be controlled. And the large volumetric image is obtained by point scanning. The simulation experiments on blood vessels was carried out to demonstrate the feasibility of the simulation plat-form. This simulation work can be used as an auxiliary tool for the research of Bessel-beam photoacoustic microscopy.