AB0870\u2005IS THE INCIDENCE OF GOUT SIMILAR TO OTHER RISK FACTORS IN PATIENTS PRESENTING WITH STROKE OR MYOCARDIAL INFARCTION?

Abstract

Background Gout is a common form of inflammatory arthritis. The prevalence of gout in Europe is between 0.9-2.5% with rates as high as 4% reported in Ireland.1 Studies have suggested gout as a risk factor in patients presenting with myocardial infarction (MI) and stroke (CVA).However the incidence gout in patients presenting to hospital with MI or CVA in Ireland has not previously been assessed. Objectives The aim of this study was to assess the incidence of gout in patients presenting with CVA and MI in Ireland. A further objective was to explore if the incidence of gout is similar to other risk factors such as hypertension, diabetes mellitus and dyslipidemia in Irish patients presenting with CVA and MI. Methods The Hospital In-Patient Enquiry Scheme ( HIPE) was used to identify patients admitted with stroke or myocardial infarction from 62 acute public hospitals in Ireland from January 2007 until December 2017. HIPE is a national database which records coded hospital admission and demographic, clinical and administrative data on discharges from, and deaths in, acute public hospitals nationally.2 Discharges are coded using the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision, Australian Modification (ICD-10-AM), Australian Classification of Health interventions (ACHI), Australian Coding Standards (ACS), 8th Edition. Age, gender and number of patient admissions with MI or CVA with gout, diabetes, hypertension, peripheral vascular disease(PVD) and hyperlipidemia were recorded. Results From 2007 until 2017, 64,867 were admitted with a diagnosis of CVA in Ireland. The age and gender of patients admitted with a principal diagnosis of CVA are outlined in Table 1. 70,628 patients were admitted with MI. In the CVA population,14.5% of patients had diabetes. Incidence of gout in patients with CVA(0.7%) was similar to patient with the risk factors of hyperlipidemia (0.91%) and PVD (0.94%). The incidence of gout in the MI group (0.5%) was lower when compared to the stroke group (0.77%). The presence of diabetes as a risk factor ( 6.7%)was significantly higher compared to gout (0.5%)in patients admitted with myocardial infarction. Chart one outlines the incidence of each risk factor in patients discharge with a primary diagnosis of MI in Ireland between 2007 and 2017 Conclusion The incidence of gout in patients presenting with CVA or MI in Ireland was low compared to other risk factors including diabetes. In patients presenting with MI then incidence of gout is lower than in patients presenting with CVA. References [1] Richette Pet al, 2016updated EULAR evidence-based recommendations for the management of gout, Ann Rheum Dis2017;76:29-42. [2] Moloney ED, et l Do consultants differ? Inferences drawn from hospital in-patient enquiry (HIPE) discharge coding at an Irish teaching hospital Postgraduate Medical Journal 2005;81:327-332.Figure 1 Disclosure of Interests None declaredAbstract AB0870 Table 1 Number of discharges with a principal diagnosis of stroke, by age group and sex, reported to HIPE, 2007-2017 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 Age Group 0-29 years 191 193 112 93 136 118 90 94 92 97 89 30-34 Years 62 53 62 65 57 65 56 54 59 56 57 35-39 Years 93 107 119 68 82 75 82 63 98 93 81 40-44 Years 141 153 134 162 152 163 125 123 131 144 158 45-49 Years 215 169 170 205 232 214 198 193 176 249 201 50-54 Years 315 293 277 284 279 299 254 307 289 309 295 55-59 Years 338 386 395 417 393 345 372 415 386 398 413 60-64 Years 467 560 523 508 500 504 492 489 559 565 505 65-69 Years 566 578 585 600 631 643 662 657 667 677 766 70-74 Years 730 709 763 677 712 682 749 782 821 838 778 75-79 Years 886 890 935 937 889 926 845 867 909 862 915 80-84 Years 967 902 975 924 860 959 878 944 912 935 927 85-89 Years 648 695 728 699 703 717 705 695 666 697 702 90 Years and over 278 315 325 363 342 388 354 352 401 411 412 Sex Male 2,988 3,066 3,107 3,087 3,071 3,174 3,032 3,198 3,368 3,413 3,499 Female 2,909 2,937 2,996 2,915 2,897 2,924 2,830 2,837 2,798 2,918 2,800 Total 5,897 5,897 5,897 5,897 5,897 5,897 5,897 5,897 5,897 5,897 5,897