POS1462-HPR\u2005VALIDITY AND PSYCHOMETRIC CHARACTERISTICS OF THE PSORIATIC ARTHRITIS QUALITY OF LIFE (PSAQOL) QUESTIONNAIRE IN TURKISH POPULATION

Abstract

Psoriatic Arthritis Quality of Life (PsAQoL) questionnaire was developed to measure quality of life (QoL) in patients with psoriatic arthritis (PsA) (1).The aim of the study was to assess validity and psychometric properties of the PsAQoL questionnaire.The translation-back translation method by a bilingual panel was used to translate the original PsAQoL into Turkish (2). Face and content validities were evaluated via cognitive debriefing interviews with 10 PsA patients. Then, patients with PsA according to CASPAR criteria were recruited to assess feasibility, missing data, floor and ceiling effect, reliability, and construct validity. Reliability was assessed by internal consistency. Construct validity was investigated by convergent and divergent validity by assessing the PsAQoL’s relations with QoL and non-QoL parameters. For this purpose, demographics, clinical characteristics (shown in Table 1), survey data including PsAQoL, Short form 36, visual analog scales for pain and fatigue, Health Assessment Questionnaire, and Hospital Anxiety and Depression Scale results were recorded.One hundred and sixty-two patients were recruited and 74 of them had axial PsA. Cognitive debriefing showed the Turkish version of PsAQoL to be clear, understandable, and relevant. It was easy to complete and calculate, with the 3 minutes and 20 seconds, respectively. The Cronbach’s alpha coefficient for internal consistency was 0.930. The questionnaire presented no floor or ceiling effect (<15% for both) and no missing data. PsAQoL showed good correlations with the QoL scales indicating its convergent validity and moderate to non-significant correlations with the non-QoL parameters supporting its divergent validity (Table 1).The Turkish version of the PsAQoL is a valid and disease-specific instrument with good psychometric characteristics to assess PsA-specific QoL.[1]McKenna SP, Doward LC, Whalley D, Tennant A, Emery P, Veale DJ. Development of the PsAQoL: a quality of life instrument specific to psoriatic arthritis. Ann Rheum Dis. 2004;63(2):162-169.[2]Beaton DE, Bombardier C, Guillemin F, Ferraz MB. Guidelines for the process of cross-cultural adaptation of self-report measures. Spine (Phila Pa 1976). 2000;25(24):3186-3191.Table 1.Spearman’s correlation coefficients of PsAQoL with the other parameters for construct validityConvergentDivergentSF-36 subscalesRhoClinical ParametersRhoSurveysRhoPhysical component-0.744**Age0.150BASDAI (n:74)0.355**Mental component-0.731**Disease duration0.014VAS Pain0.408**Physical functioning-0.629**Tender joint count0.262**VAS Fatigue0.447**Physical role limitations-0.640**Swollen joint count0.170*HAQ0.533**Emotional role limitations-0.576**MASES0.152HADS Anxiety0.535**Vitality-0.657**PASI-0.032HADS Depression0.517**Emotional well-being-0.590**DAPSA0.409**Social functioning-0.591**DAS280.322**Pain-0.535**BASMI (n: 61)0.032General health-0.536**** p<0.001, *p: 0.001-0.049.PsAQoL: Psoriatic Arthritis Quality of Life, SF-36: Short Form 36, MASES: Maastricht Ankylosing Spondylitis Enthesitis Score, PASI: Psoriasis Area Severity Index, DAPSA: Disease Activity in PSoriatic Arthritis, DAS28: Disease Activity Score 28, BASMI: Bath Ankylosing Spondylitis Metrology Index, BASDAI: Bath Ankylosing Spondylitis Disease Activity Index, VAS: Visual analog scale, HAQ: Health Assessment Questionnaire, HADS: Hospital Anxiety and Depression Scale.None declared