BMJ Case Reports | 2021
Gastropleural fistula: a rare complication of a perforated gastric ulcer in a hiatus hernia
Abstract
© BMJ Publishing Group Limited 2021. No commercial reuse. See rights and permissions. Published by BMJ. DESCRIPTION A woman in her late 60s presented to hospital with a 1day history of lethargy, confusion and worsening abdominal pain. This was on a background of several weeks of leftsided abdominal pain. There was no history of vomiting or haemoptysis. Her history included chronic renal impairment (baseline estimated glomerular filtration rate 16), and a known large hiatus hernia with Cameron erosions (identified on gastroscopy 6 months prior). She was experiencing gradual functional decline over the preceding months. On arrival, she was critically unwell. She was hypothermic (35°C), tachycardic (140/min), hypotensive (70/45 mm Hg), hypoxic (SpO2 94% on highflow oxygen), tachypnoeic (36/min) and had a Glasgow Coma Scale score of 12. On examination, she was peripherally shut down and had decreased air entry to the entire left chest. Her abdomen was soft and nontender. She received intravenous fluid resuscitation, was commenced on an adrenaline infusion and received broadspectrum antibiotics/ antifungals. Bloods revealed haemoglobin 82g/L, white cell count 27.5x10/L, C reactive protein 213, K 7.6 and eGFR 8. COVID-19 PCR later returned negative. An Xray of the chest showed complete whiteout of left lung with significant mediastinal shift (figure 1). A CT of the chest/abdomen/pelvis showed a large left hydropneumothorax causing compressive mass effect on the heart and mediastinal structures and some free gas anterior to the aorta (figure 2). She was intubated in the intensive care unit and commenced on noradrenaline and argipressin infusions. A left intercostal catheter (ICC) was placed into the left pleural cavity with 1.5 L of gastric contents drained. A nasogastric tube was inserted. Her ionotropic requirement progressively increased, and she continued to have progressive renal impairment despite haemofiltration. A family meeting was held with the consensus being that proceeding with invasive and difficult surgical intervention was unlikely to result in a favourable outcome. Care was withdrawn and the patient passed away the same day. A gastropleural fistula is an abnormal communication between the stomach and the pleural cavity. Gastropleural fistula due to intrathoracic gastric perforation in a hiatus hernia is exceptionally rare, with the incidence currently unknown. A limited number of cases dating back to the 1950s have been reported. All reported cases proved to be fatal, with our case being no exception. The diagnosis is suspected when gastric fluid is obtained post insertion of an ICC. Pleural fluid analysis can be requested if there is any diagnostic uncertainty. While there are no hallmark signs of imaging, the presence of hydropneumothorax and pneumomediastinum are key diagnostic features,