The Fractional Differential Model of HIV-1 Infection of CD4+ T-Cells with Description of the Effect of Antiviral Drug Treatment

Abstract

In this paper, the fractional-order differential model of HIV-1 infection of CD4+ T-cells with the effect of drug therapy has been introduced. There are three components: uninfected CD4+ T-cells, x, infected CD4+ T-cells, y, and density of virions in plasma, z. The aim is to gain numerical solution of this fractional-order HIV-1 model by Laplace Adomian decomposition method (LADM). The solution of the proposed model has been achieved in a series form. Moreover, to illustrate the ability and efficiency of the proposed approach, the solution will be compared with the solutions of some other numerical methods. The Caputo sense has been used for fractional derivatives.