Analysis of the Effect of Intra-Articular Injection of Platelet-Rich Plasma on Knee Arthritis Pain Based on MRI Image Segmentation Algorithm

Abstract

Objective: To study the effect of bone marrow platelet-rich plasma (PRP) injection on osteoarthritis using a level set-based MRI image segmentation algorithm. Methods: 180 patients with knee osteoarthritis (206 knees) were randomly divided into observation group (92 knees)\n and control group (88 knees). The observation group was injected with 2 mL of enriched stem cells and PRP suspension in the joint cavity, and then injected once again after 6 weeks. The control group was injected with 2 mL of sodium hyaluronate in the joint cavity, once a week for a total\n of 5 times. After 3 months and 6 months of treatment, the patients were followed up, and the clinical efficacy of the two groups was evaluated by the WOMAC score. The MRI image segmentation of the patients was analyzed using the level set-based MRI image segmentation method. Results:\n The WOMAC score observation group was 45.88 ± 9.54 points before treatment, 25.26 ± 6.67 points 3 months after treatment, 22.44 ± 5.19 points 6 months after treatment; the control group was 46.76 ± 8.06 points before treatment and 32.12 ± 5.35 3 months after\n treatment. Points, 33.34 ± 6.32 points 6 months after treatment. The WOMAC score of the observation group and the control group was improved after treatment, and the difference was statistically significant (P < 0.05) compared with that before treatment. Conclusion:\n The observation group has a clear effect on the treatment of knee osteoarthritis and is worthy of clinical application.