Smoking-Specific Risk Factors in Early Adulthood That Mediate Risk of Daily Smoking by Age 29 for Children with ADHD.

Abstract

OBJECTIVE\nTo test whether smoking-specific risk factors in early adulthood mediate prediction to daily smoking from childhood ADHD.\n\n\nMETHODS\nParticipants were 237 with and 164 without childhood ADHD. A smoking risk profile score comprising smoking-specific factors measured between ages 18 to 25 (e.g., craving severity) and age of initiation was tested as mediator of the association between childhood ADHD and age 29 daily smoking.\n\n\nRESULTS\nChildhood ADHD predicted age 29 smoking (β\u2009=\u2009-.15, p\u2009=\u2009.019), 35% of ADHD versus 17% of nonADHD, and the profile score (β\u2009=\u2009-.07, p\u2009=\u2009.004), which in turn mediated prediction to age 29 daily smoking (β\u2009=\u2009-.03; p\u2009=\u2009.007). When tested individually, three profile variables (# cigarettes/day, difficulty concentrating during abstinence, and nicotine dependence) were significant mediators (ps\u2009=\u20090.005-0.038), above and beyond early adult smoking, ADHD persistence, and delinquency.\n\n\nCONCLUSIONS\nThese behavioral smoking characteristics help explain later daily cigarette smoking for adults with ADHD histories and may need to be targeted in intervention.