Restless legs syndrome

Abstract

Restless legs syndrome is a common, often debilitating disorder, which is under-recognised and under-diagnosed. Patients typically describe an uncomfortable urge to move their legs, this occurs mainly at night. It often has a significant impact on the quality of sleep, and hence, daily functioning. The pathophysiology of the disorder is well known, it relates to iron depletion and dopaminergic receptors in the brain, and this has aided the development of effective treatment. This article will cover the recognition, pathophysiology and management of the condition.