A rare case: Mania associated with pazopanib

Abstract

Mania typically presents with a well-denoted period of abnormal and persistently elevated or irritable mood, and increased activity or energy almost daily for at least a week. This mood disturbance is usually functionally dilapidating in aspects of social or occupational functioning, sometimes even requiring hospitalisation to prevent harm to self or others. We report an interesting case of first presentation of mania in a 61-year-old female with ongoing metastatic sarcoma, with a potential association with a chemotherapy drug – pazopanib.