Retrospective comparative clinical study for silk mat application into extraction socket

Abstract

BackgroundSilk mats have been approved for clinical trials by the Korean Food and Drug Administration as membranes for guided tissue regeneration (GTR). In this study, silk mat application was compared to high-density polytetrafluoroethylene (dPTFE) membrane application or no membrane group.MethodsTo compare the silk mat group to the dPTFE group or the no membrane group, a retrospective sample collection was conducted. Bony defects were measured at the time of extraction (T0) and then at 3\u2009months (T1) and 6\u2009months after extraction (T2) on a digital panoramic view. Bone gain (BG) was calculated by subtracting from the bony defect at T0 to the bony defect at each follow-up.ResultsThe BG at T2 was 2.44\u2009±\u20092.49\u2009mm, 4.18\u2009±\u20091.80\u2009mm, and 4.24\u2009±\u20092.05\u2009mm in the no membrane group, silk mat group, and dPTFE group, respectively. Both membrane groups had significantly higher BG than BG in the no membrane group at T2 (P\u2009<\u20090.05).ConclusionsBoth membrane groups showed higher BG than the no membrane group.