Phase I study of BJ-001, a tumor-targeting interleukin-15 fusion protein, in patients with solid tumor.

Abstract

e14545Background: BJ-001 is the first tumor-targeting Interleukin-15 (IL-15) fusion protein, composed of an integrin-binding Arg-Gly-Asp (RGD)-4C motif, linked with a human IgG1 Fc, and then a modi...