Copper(I)-mediated C–N/C–C Bond-forming Reaction with Tetrafluoroethylene for the Synthesis of N-Fluoroalkyl Heteroarenes via an Azacupration/Coupling Mechanism

Abstract

A novel copper(I)-mediated C–N/C–C bond-forming reaction involving tetrafluoroethylene (TFE), imidazolide or benzimidazolide salts, and aryl iodides has been developed. This three-component couplin...