The Unknown Equal Variance Model of Bivariate Meta-Analysis Based on the Difference Mean

Abstract

This paper introduces the unknown equal variance model of bivariate Meta-analysis based on the difference mean. We obtain the maximum likelihood estimator of the difference mean effect and unknown variances; then we find the combining overall difference mean effect overall D by the fixed-effect model of bivariate Meta-analysis based on the difference mean. Moreover, we obtain the corresponding covariance matrix and the ( ) 1 100% −α confidence interval for the overall difference mean effect overall D .