F1000Research | 2021

Modeling the impact of early interventions on the transmission dynamics of coronavirus infection

 
 
 

Abstract


A deterministic model is proposed to describe the transmission dynamics of coronavirus infection with early interventions. Epidemiological studies have employed modeling to unravel knowledge that transformed the lives of families, communities, nations and the entire globe. The study established the stability of both disease free and endemic equilibria. Stability occurs when the reproduction number, R0, is less than unity for both disease free and endemic equilibrium points. The global stability of the disease-free equilibrium point of the model is established whenever the basic reproduction number R0 is less than or equal to unity. The reproduction number is also shown to be directly related to the transmission probability (β), rate at which latently infected individuals join the infected class (δ) and rate of recruitment (Λ). It is inversely related to natural death rate (μ), rate of early treatment (τ 1), rate of hospitalization of infected individuals (θ) and Covid-induced death rate (σ). The analytical results established are confirmed by numerical simulation of the model.

Volume 10
Pages None
DOI 10.12688/f1000research.54268.2
Language English
Journal F1000Research

Full Text