Relationship of Servo Pressure in High Frequency Jet Ventilation in Lung Models with Variable Compliance for Neonates

Abstract

Introduction High Frequency Jet Ventilation (HFJV) has been shown to improve oxygenation and ventilation in premature neonates with respiratory distress syndrome and in those with evolving chronic lung disease. Higher positive end expiratory pressure (PEEP) use in HFJV has been associated with improving lung compliance and reducing ventilator requirements. Servo pressure in HFJV is the driving pressure required to regulate flow. In general, increased resistance and decreased compliance generate lower servo pressure. Lung volumes also affect servo pressure. Servo pressure variability in HFJV has not been studied. We aim to study changes in servo pressures for variable compliance …