Treatment of cancer patients during COVID-19 pandemic

Abstract

Background Cancer patients comprise one of the most vulnerable subpopulations under COVID-19 pandemic, since the incidence of COVID-19 among cancer patients exceeds this value in general population Risk of severe COVID-19 infection and mortality is higher in patients with cancer Objective Searching and retrospective analysis of risk factors of mortality in cancer patients with COVID-19 infection Material and methods A retrospective analysis included 31 cancer patients who underwent surgery at the Herzen Moscow Oncology Research Institute COVID-19 was detected in postoperative period in each patient We have compared survivors and non-sur-vivors and assessed the risk factors of mortality Results COVID-19 in postoperative period occurred in 31 (4 74%) out of 722 patients Hypertension (74 2%, n=23) and car-diac diseases including coronary artery disease and chronic heart failure (19 35%, n=6) were the most common comorbidi-ties Incidence of coronavirus infection was the highest among patients with colorectal cancer (16 13%, n=5), kidney cancer (16 13%, n=5) and lung cancer (12 9%, n=4) We found the following risk factors of mortality in cancer patients with COVID-19: CHD (OR 7 0, 95% CI 1 014-48 313, p<0 05), COPD (OR 15 000, 95% CI 1 397-161 052, p<0 05), lung cancer (OR 12 000, 95% CI 1 074-134 116, p<0 05), and mechanical ventilation (OR 135 000, 95% CI 7 485-2435 007, p<0 05) © 2021, Media Sphera All rights reserved