Archive | 2019
Эффективность меполизумаба при длительной терапии тяжелой эозинофильной бронхиальной астмы (клинические наблюдения)
Abstract
Two clinical cases of severe eosinophilic asthma taking long-term\xa0 therapy with mepolizumab\xa0 (38 and 45 months are described in the article. Both the cases demonstrate\xa0 the effectiveness of the drug both in allergic and non-allergic\xa0 (aspirin-induced) asthma. Significant clinical improvement\xa0 was achieved in both cases under the treatment with mepolizumab\xa0 during ≥ 3 years. Important results of the treatment were improvement\xa0 in symptoms of severe asthma, reduction in exacerbation rate, and, additionally,\xa0 overcoming corticosteroid\xa0 addiction in patients. The therapy with mepolizumab was highly safe.