Adherence to treatment in patients undergoing dialysis

Abstract

CKD is defined as abnormalities of kidney structure or function, present for >3 months, with implications for health and CKD is classified based on cause, GFR category, and albuminuria category (CGA). Based on GFR CKD is classified as G1 that is GFR is normal or high (≥90 ml/min/1.73 mm); G2-Mildly decreased (60-89 ml/min/1.73 mm); G3aMildly to moderately decreased (45-59 ml/min/1.73 mm); G3bModerately to severely decreased (30-44 ml/min/1.73 mm); G4Severely decreased (15-29 ml/min/1.73 mm); G5Kidney failure (15 ml/min/1.73 mm). Dialysis should be initiated when one or more of the following are present: symptoms or signs attributable to kidney failure (serositis, acid-base or electrolyte abnormalities, pruritus); inability to control volume status or blood pressure; a progressive deterioration in nutritional status refractory to dietary intervention; or cognitive impairment. This often but not invariably occurs in the GFR range between 5 and 10 ml/min/1.73 m. Given the difficulties in diagnosing ESRD, the presence of estimated GFR <15 mL/min/1.73m itself has been suggested as an end point. To define ESRD, two criteria must be fulfilled: ABSTRACT