Predictive value of uterine artery: peak systolic velocity on the day of trigger for clinical pregnancy rate in infertile women

Abstract

The World Health Organization (WHO) estimates that approximately 8%-10% of couples experience infertility problem due to various explained and unexplained reasons. In vitro fertilization and embryo transfer (IVFET) is endorsed and is selectively and readily available for the management of infertility. The most exasperating problem with the IVF-ET is implantation failure, which decreases the treatment success rate to 15-45%. The pregnancy outcome depends upon diverse aspects related to IVF cycles. 30% of infertile partners in the world have been diagnosed as unexplained / idiopathic infertility and this is defined as “the lack of an obvious cause for a couple s infertility and the females’ inability to get pregnant after at least 12 cycles of unprotected intercourse or after six cycles in women above 35 years of age for whom all the standard evaluations are normal”. A receptive endometrium is necessary for successful implantation Endometrial blood flow reflects the receptivity of endometrium since implantation takes place in endometrium. Uterine perfusion and its impedance have been found to be an indicator for the likelihood of subsequent implantation. Uterine artery Doppler has been used as marker to predict chances of pregnancy. Impaired perfusion of uterine artery can lead to unsuccessful IVF treatment therefore probably a cause of infertility. Colour Doppler can be used to asses Uterine artery blood flow velocimetry. The advent of transvaginal ultrasound with 2D and 3D power Doppler ABSTRACT