A prospective study to assess the use of preoperative neutrophil to lymphocyte ratio as a predictor of severe cholecystitis

Abstract

The prevalence of severe cholecystitis has been found to be 22-30% in surgical series. According to the degree of inflammation, cholecystitis can be divided into simple and severe cholecystitis. Untreated simple cholecystitis resolves within 7–10 days if it does not progress to more severe cholecystitis. The severe forms of cholecystitis include secondary changes such as hemorrhage, gangrene, emphysema, xanthogranuloma, and perforation. Patients with severe cholecystitis usually require a higher number of intensive care unit admissions, prolonged postoperative hospital stays, and have increased morbidity and mortality. Delayed management can lead to increased morbidity due to progression to severe disease such as gangrenous change, abscess formation and gall bladder perforation.