International Surgery Journal | 2019
Role of platelet to lymphocyte ratio in assessing prognosis in acute pancreatitis
Abstract
Acute Pancreatitis (AP) is defined as an acute condition presenting with abdominal pain, a threefold or greater rise in the serum levels of the pancreatic enzymes amylase or lipase, and/or characteristic findings of pancreatic inflammation on contrast enhanced CT. It is an inflammatory process in which local pancreatic injury leads to systemic inflammation through activation of cytokine cascades. The clinical extent of acute pancreatiits varies widely from no symptoms to systemic inflammatory response syndrome (SIRS), persistent organ failure (POF), and death. The clinical signs of acute pancreatitis may be nonspecific and they exhibit a low sensitivity (40%) for the prediction of an adverse outcome. Various severity scoring systems has been ABSTRACT