Prevalence and clinical correlates of neonatal thrombocytopaenia in a tertiary healthcare facility in a low-income country

Abstract

Thrombocytes (platelets) are important blood components primarily involved in haemostasis (to prevent excessive bleeding). Thrombocytopaenia is a state of reduced circulating platelet count in blood below normal level. It is defined as platelet count less than 150×10/L and sometimes, as less than 100×10/L.1 It is considered severe if platelet count is below 30×10/L, moderate if it is between 30×10/L and 50×10/L and mild (usually asymptomatic) if above 50×10/L. It is also commonly classified as early (within the first 72 hours of life) or late (after 72 hours). The prevalence of thrombocytopaenia among neonates admitted into special care baby units (SCBU) ranges between 6% to 35%. Thrombocytopaenia complicates illnesses in the neonate with significant impact on morbidity and mortality. The ABSTRACT