Evaluation of Central Corneal Thickness and clinical ocular profile of Patients presenting with Pseudoexfoliation at a tertiary care centre

Abstract

Introduction: Pseudoexfoliation syndrome is the most common identifiable cause of open angle glaucoma\nworld-wide. It is a systemic disorder with important eye manifestations.\nAims: To compare central corneal thickness (CCT) in pseudoexfoliation syndrome (PEX) and\npseudoexfoliative glaucoma (PXG) with the normal eyes.- To document ocular profile of PEX and PXG\nMaterial and Methods: cross- sectional, hospital based observational study done from November 2018-\nMay 2019. Sixty-five patients each in PEX and PXG were included for detailed study. To compare CCT,\n65 age matched normal subjects were enrolled.\nResults and Conclusion: The prevalence of PEX and PXG increases with age. It was predominantly\nseen in males. Most of the patients had bilateral presentation, with PEX material most commonly\nfound at pupillary margins. Open angle in most patients but presence of narrow angles in PXG group\nwas statistically significant than PEX. CCT was thinner in both PEX and PXG than normal which\nwas statistically significant. Twenty-one patients in PXG group underwent combined cataract surgery and\ntrabeculectomy owing to high pressure and advanced optic neuropathy.\n\nKeywords:\xa0Pseudoexfoliative glaucoma\xa0central corneal thickness\xa0intraocular pressure.