journal of medical science and clinical research | 2019
Von Recklinghausen Disease with Vitiligo: A Rare Association
Abstract
1 Professor and Head, 2,6 Post graduate student, 3 Senior Resident, 4 Associate Professor, 5 Assistant Professor, Deptt. of Dermatology, Leprosy and Venereology, Indira Gandhi Medical College, Shimla, Himachal Pradesh *Corresponding Author Saru Thakur Deptt. of Dermatology, Leprosy and Venereology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India Abstract Von Recklinghausen disease, also known as neurofibromatosis 1 is one of the commonest neurocutaneous disorders. It is associated with an increased risk of developing benign and malignant tumors. However, only few case reports are mentioned in literature associating neurofibromatosis with autoimmune disorders, vitiligo being one of them. We report a case of 30 years old female, who presented with cutaneous features of neurofibromatosis 1 and vitiligo. Interestingly, she had multiple neurofibromas, which were characteristically depigmented. Only few case reports have been mentioned in literature associating these two disorders. Whether this exists due to some underlying genetic defect of NF1 gene or mere coincidence, it is yet to be found.