Respiratory syncytial viral infection in a child with genetic pathology

Abstract

The relevance of respiratory syncytial virus infection is due to its widespread, severity of the course in young children with a predominant lesion of the lower respiratory tract with acute respiratory failure and absence of etiotropic therapy with proven efficacy. The risk group for severe course and mortality is made up of premature babies, children with bronchopulmonary dysplasia, hemodynamically significant congenital heart disease. In addition, according to individual indications, by the decision of the council, specific prophylaxis is carried out for newborns and premature infants with severe neuromuscular pathology, CNS injury with impaired respiratory function, patients with congenital anomalies and genetic pathology of the respiratory system, as well as congenital immunodeficiency. The article presents a description and analysis of the severe course of respiratory syncytial infection with the development of obstructive bronchitis with respiratory failure of the 2nd degree in a child aged 1 year 4 months with Charge syndrome – a severe genetic pathology, including combined congenital heart disease, choanal artesia, protein-energy malnutrition, congenital immunodeficiency. The child had bronchopulmonary dysplasia, chronic paralytic laryngeal stenosis. The disease required oxygen support and the patient s stay in the intensive care unit. The described clinical example demonstrates a severe course of respiratory syncytial virus infection with the damage of the lower respiratory tract in a child over one year old from the risk group. Key words: respiratory syncytial virus infection, children, obstructive bronchitis, bronchiolitis