Granular cell tumor of the abdominal wall, a case report and review of literature.

Abstract

Granular cell tumors (GCTs) on the abdominal wall are rare and present as a painless superficial abdominal mass. We report the case of a 73-year-old female, who presented to the family medicine practice with a painless subcutaneous anterior abdominal wall mass. Ultrasound showed a 0.9×0.5×1.3 cm3 hyperechoic solid lesion with distal shadowing within the subcutaneous tissue of the anterior abdominal wall. The X-ray did not show any calcification within the subcutaneous tissue which ruled out metastatic calcified lesions. The patient was referred to general surgery for further evaluation. A previous computed tomography (CT) revealed a nonspecific 12 mm lesion involving the skin and subcutaneous fat in the right upper quadrant of the anterior abdominal wall. The lesion was excised under local anesthesia and sent for histopathological analysis. CD68 highlighted the multitude of macrophages microscopically. Histopathology demonstrated CKAE1/AE3 was negative for any epithelial components and S100 was diffusely positive. A final diagnosis of GCT was made. On follow-up, the patient underwent excision of the scar tissue with no evidence of atypia or GCT. This case is unique due to its benign presentation and limited reported literature. Further evaluation of a painless subcutaneous lesion is imperative to rule out rare conditions and the possibility of recurrent or metastatic malignancy.