Surgical repair of concomitant ventricular septal defect and aortic cusp prolapse or aortic regurgitation, also known as the Laubry-Pezzi syndrome.

Abstract

It has been almost a century since Charles Laubry and Cesare Pezzi first described the clinical features of aortic regurgitation (AR) due to aortic valve prolapse in patients with ventricular septal defects (VSDs) (1). The Venturi effect is the explanation to Laubry-Pezzi syndrome: a significant fall in pressure when blood flows through the VSD under the aortic valve, sucking either the right or the non-coronary leaflet in the VSD, resulting in AR. It is most commonly found in infundibular VSDs but can also be encountered with perimembranous VSDs.