Возрастные аспекты заболеваемости хроническим вирусным гепатитом С у детей

Abstract

Purpose of the study: to reveal characteristics of chronic viral hepatitis C (HCV) incidence in babies and preschoolers, schoolchildren, teenagers on the example of the Nizhny Novgorod region. Materials and methods. The article presents official epidemiological information on the incidence of HCV in children in the Nizhny Novgorod region in 1995–2015. Data statistical processing was performed with Statistica 7.0. soft ware package. Zero hypotheses were rejected at significance level of the corresponding statistical criterion p < 0,05. Results. The study revealed differences of HCV-epidemic process in infants and preschoolers, schoolchildren and teenagers. The incidence of HCV in children 0–6 years old and 15–17 years old is characterized by a lack of reduction and an uncertain prognosis (p < 0,05); the positive prognosis is possible in schoolchildren aged 7–14 years (p < 0,05). There was an increase of patients of younger age groups in the proportion, and decrease of cases frequency in children 7–14-year-olds. The authors identified that the viral hepatitis C incidence is correlate with the public health indicators and with the health care institutions activities; the correlations strength and correlations pattern is depend on age. The article presents a quantitative assessment of the relationship between the children HCV incidence in different age periods and the public health indicators and activities health institutions. Conclusions. In HCV-epidemic process in children at the present there is a redistribution of older and younger age groups role in its maintenance with the leading significance of the latter. Obtained results prove the significant contribution of HCV positive women of fertile age in the HCV- epidemic process in children at the present stage.