Areca Catechu Leaf Extract-Mediated Synthesis of Stabilized Silver Doped-Copper Oxide Nanoparticles and its Biomedical Applications

Abstract

\n The current research work gives an insight into the green synthesis of metallic nanoparticle using medicinally important plant, which has gained increasing applications in therapeutics and medicinal science. Herein, we describe an eco-friendly method to synthesize Ag- CuO nanoparticles using Areca catechu leaf extract via solution combustion method. Crystalline structure, size and surface morphology of the synthesized nanoparticles were confirmed by X-ray diffraction (XRD), Scanning Electron Microscopy (SEM), Energy Dispersive Spectroscopy (EDS), Transmission Electron Microscopy (TEM) and Fourier Transformer Infrared Spectroscopy (FTIR). XRD patterns of the as-prepared Ag-CuO NPs revealed that they possess monoclinic crystalline structure. The morphology and the elemental composition was found by SEM-EDS and TEM analysis, which revealed the nano-spherical shape of Ag-CuO NPs. Further, the Ag-CuO NPs were tested for Antidiabetic activity by using Yeast cell model and amalyze inhibition, which showed promising antidiabetic activity. In addition, the as-prepared material displayed significant anticancer activity against MCF-7 cancer cell line.