Mobile Health Applications Interventions For Prediabetic State: Protocol of Systematic Review

Abstract

\n Background: Individuals with prediabetic state are much more likely to develop Type-2 Diabetes Mellitus (TD2M) 4 times greater than those with normal glucose tolerance. Lifestyle changes such as daily physical activity and healthy diets can decrease the risk of prediabetic state . Mobile applications intervention could be one of the solutions to improve self-management awareness and compliance of prediabetic state intervention. There are no studies in systematic reviews of mobile phone applications intervention to prevent prediabetic state yet. Therefore, the objective of this study was to collect and summarize the evidence from randomized controlled trials (RCTs) exploring the effectiveness of mobile phone applications for intervention in prediabetic state patients.Methods: This protocol was prepared in accordance with the preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) statement. The database that will be used includes PubMed, ProQuest and EBSCO with date restriction between January 2007 and July 2019 in English language only. Identification of articles will be done independently by three reviewers through the title of the articles, reviewing the abstract, and then the full-text-article. Any disagreement will be resolved by consensus. The quality assessment and possible risk of bias will be evaluated using forms adapted from the Jadad score. Extraction and content analysis will be performed systematically. Quantitative data will be presented graphically via forest plot with 95% confidence intervals. Where possible we will explore the heterogeneity and continue to conduct meta-analysis using RevMan software package. Discussion: Changes in lifestyle, such as daily physical activity and a nutritious diet, can help to reduce the risk of prediabetes. Mobile phone applications, including health-related applications, is demonstrated to have a lot of promise in terms of providing tailored medical recommendations. Conclusion: The proposed systematic review and meta-analyses will allow us to obtain the evidence exploring the effectiveness of mobile phone applications for intervention in prediabetic state patients.Systematic review registration: This protocol has been registered in the Prospective Registry of Systematic Review (PROSPERO) database (CRD42021243813).