Analysis of the Fluid Contents of Simple Bone Cyst in the Mandible: Blood or Serum?

Abstract

\n Description of the content of simple bone cyst (SBC) has been controversial. This study aimed to evaluate and give a clearer picture of the contents of the SBC cavity. Nineteen patients SBC confirmed by histopathological examination, between 2014 and 2016, were included in this study. The clinical, radiographic, surgical and laboratory findings of SBC cavity content was analyzed. For statistical analysis, paired samples t-test was used to evaluate the difference of components among cavity fluid, blood and serum. All 19 SBC cases radiographically and surgically revealed a fluid-filled cavity. The average age of the patients was 21.3±13.2 years. Any sex predominance was not found. SBCs were more often found in the anterior mandible site (n=12, 63.2%). All lesions were filled with clear straw-colored or low concentrated blood-colored flood. Although the laboratory analysis of the fluid showed components similar to those in blood and serum, the statistical analysis showed that the fluid components were not significantly different only for eosinophils (p = 0.43) and basophils (p = 0.06) counts as blood components, and sodium (p = 0.76), potassium (p = 0.08) and chloride (p = 0.13) concentration as serum components. Within a limitation of this study, the results shows that SBC is fluid-filled cavity and the cavity fluid is more likely similar to the serum rather than the blood regarding the internal components.