EFFECT OF ONLINE HEMODIAFILTRATION ON PATIENTS WITH SEPSIS AND ACUTE KIDNEY INJURY IN INTENSIVE CARE UNIT

Abstract

Background: Acute kidney injury is a common occurrence in critically ill patients, with incidence rates of occurrence varying from 5 to 60% and a trend towards higher rates (30 to 60%) when using the risk, injury, failure, loss of kidney function, end stage renal failure (RIFLE) or Acute Kidney Injury (AKI) Network (AKIN) classification. Objective: To compare between effect of online hemodiafiltration and conventional hemodialysis in patients with sepsis and acute kidney injury in intensive care unit. Patients and Methods: This study included forty (age and sex matched) patients with acute kidney injury (AKI) who were critically ill they were selected from the Nephrology Unit Ahmed Maher Teaching Hospital. The included patients were divided into two equal groups: Group (A) that included patients on online hemodiafiltration (OLHDF) and Group (B) that included patients on conventional hemodialysis. Results: There was a statistically significant difference found between two groups after dialysis regarding HB, WBCs, platelet, Na and albumin. Also, there was high statistically significant difference between two groups regarding urea, creat, K and PCT, and there was no statistically significant difference between the two groups regarding CRP. Conclusion: OL-HDF showed to be better than IHD-LI in many aspects but there was no statistically significant difference in mortality.