The Weight Assessment and its Relation to Hemophilia Joint Health Score in Hemophilic Patients

Abstract

Background: Haemophilia is a group of hereditary disorders that impair the body s ability to control blood clotting or coagulation. Joint bleeding (hemarthrosis) results in synovial hypertrophy and damage of the cartilage, leading to joint destruction with recurrent bleeding episodes (hemophilic arthropathy). \nObjective: To assess weight of hemophilic children and correlate the weight to Hemophilia Joint Health Score. \nMethods: The sample size included was 66 patients with hemophilia in Zagazig city between October 2019 and March 2020. They were categorized according to presence of arthropathy or not [Two groups; one group with hemophilic arthropathy and the other group without hemophilic arthropathy]. All patients were subjected to full history taking including personal history, thorough clinical examination [assessment of vital signs and color, assessment of any bone deformity, pain or muscle weakness and Hemophilia Joint Health Score ] and weight assessment, \nResults: Our case control study showing male predominance in both groups. In hemophilic arthropathy, 100% (10.68 ± 4.28) and without hemophilic arthropathy 97% (7.17 ± 4.12) and more prevalence of hemophilia A [factor V111 deficiency] in both groups (with H.A.97% & without H.A.78.8%). In addition, our study reported that most common site of bleeding in hemophilic patients rather than big joints affection; gum [18.2%] then gum & teeth [12.1%]. Increased weight was found more in hemophilia with arthropathy than in hemophilia without arthropathy. \nConclusion: Our case control study showing male predominance and more prevalence of hemophilia A than B in both hemophilic groups (with or without hemoarthropathy). Weight was significantly increased in hemophilia with arthropathy group than in hemophilia without arthropathy group.