Fungal Infection in Cystic Fibrosis

Abstract

\n\nThe prevalence of fungal infections has been increasing in recent years.\nCystic fibrosis (CF) is a genetic disorder that affects organs such as the intestines, liver, pancreas,\nand especially the lungs.\n\n\n\nFungal pathogens are becoming a challenge in CF. Advanced medical science is associated\nwith longer life expectancy in some patient groups.\n\n\n\nA review was conducted on studies found on online databases, including Google Scholar,\nPubMed, and Scopus. Internet-based searches were performed on these databases for cystic fibrosis,\nrespiratory infections, and fungal infection profiling to identify all relevant studies published\nbetween 2010 and 2020.\n\n\n\nFungal pathogens most frequently isolated from the respiratory tract include the Aspergillus\ngenus, the Candida genus, Scedosporium apiospermum, and the Rasamsonia genus. In cystic fibrosis,\nthese organisms usually colonize the respiratory and intestinal tracts and cause hypersensitivity\nresponses and invasive diseases.\n\n\n\nFungus-patient interactions are complicated and depend on various factors. Moreover,\nthe emergence of drug-resistant species is a serious health issue, and the development of new treatments\nis crucial.\n