Current cardiology reviews | 2019
Cardiovascular and renal outcomes of incretin-based therapies: A review of recent clinical trials.
Abstract
BACKGROUND\nTo report the cardiovascular and renal effects of incretin-based therapies.\n\n\nMETHOD\nThe studies of clinical trials on incretin-based therapy published in medical journals from years 2010 to 2017 were comprehensively searched using MEDLINE and EMBASE with no language restriction. The studies were reviewed and the cardiovascular and renal risks reported were recorded.\n\n\nRESULTS\nIncretin-based therapeutics represent novel and promising anti-diabetes drugs, the direct cardiovascular actions of which may translate into demonstrable clinical benefits on cardiovascular outcomes. Furthermore incretin-based therapies do not adversely affect renal function.