Racial and ethnic minority patient participation in N-of-1 trials: perspectives of healthcare providers and patients.

Abstract

Aim: Patients from racial and ethnic minority backgrounds in the USA have historically been under-represented in research trials. Understanding their viewpoints regarding participation in N-of-1 trials is imperative as we design and implement these studies. Materials & methods: We conducted six\xa0focus groups of racial and ethnic minority patients (n\xa0=\xa025) and providers (n\xa0=\xa09). We used content analysis to identify themes. Results: Our results noted the importance of considering family members in N-of-1 trial recruitment and participation, patients \xa0desire for education as a design feature, for lifestyle \xa0changes as a treatment option and for use of nonevidence-based treatments in the design of future N-of-1 trials. Conclusion: Personalized trials have the potential to change the way we deliver primary care and improve disparities for minorities.