CHARACTERIZATION AND ANTIBIOTIC SENSITIVITY OF BACTERIA IN OROFACIAL ABSCESSES OF ODONTOGENIC ORIGIN

Abstract

Background:\xa0Odontogenic infections vary from minor abscesses to superficial and deep infections that lead to acute infections in the head and neck area that may threaten the patient s life.\xa0 The objectives of this study are to identify bacteria accountable for orofacial infection of odontogenic origin and patterns of their susceptibility to drugs in order to provide a superior understanding of dental infection management in Yemen. \nMethods:\xa0 The study was conducted on a selected group of patients, regardless of gender and age, who suffer from severe to moderate orofacial infections of odontogenic origin and were admitted to the dental clinic at the Republican University Hospital in Sana a city. Sample of pus was collected and the bacteria were identified by cultivation in suitable medium and then identified by standard bacteriological techniques. Antimicrobial susceptibility testing was also performed using the Kirby-Bauer disc diffusion method. \nResult:\xa0 A total of 118 cases were positive for bacterial culture, 63 males and 55 females ranged between 5 and 65 years of age, most of them in the age group> 45 years (39.8%), 51.7% had dental abscesses and 48.3% had periodental abscesses. Staphylococcus aureus, Bacteroides species and Staphylococcus epidermidis were isolated from patients with dental abscesses, Staphylococcus aureus, Bacteroides species, Staphylococcus epidermidis and Streptococcus pyogens\xa0 from perio-Dental abscesses. The most prevalent bacteria were Staphylococcus aureus (about 63% of the total isolates), more than 40% of which were resistant to ceftizoxime, calithromycin, augmentin, tetracyclines, erythromycin and oxacillin. While Staphylococcus\xa0 epidermidis showed less antibiotic resistance than Staphylococcus aureus. As for the Bacteroids species, it was sensitive to metronidazole and clindamycin (100%), augmentin (98.6%), calrithromycin (94.4%) and finally vancomycin (76.1%).\xa0 \nConclusion:\xa0An elevated occurrence of bacterial isolates was discovered, and Staphylococcus aureus was dominant.Most of the isolated bacteria were resistant to diverse classes of antibiotics. Appropriate antibiotics should be administered based on the bacterial isolates, culture sensitivity, and clinical course of disease. \n\xa0 \xa0 \nPeer Review History: \nReceived 6 November 2020; Revised 22 Decembe; Accepted 5 January, Available online 15 January 2021 \nUJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. \nReceived file:\xa0 Comments of reviewer(s): \xa0 \nAverage Peer review marks at initial stage: 6.0/10 \nAverage Peer review marks at publication stage: 8.0/10 \nReviewer(s) detail: \nDr. Gulam Mohammed Husain, National Research Institute of Unani Medicine for Skin Disorders, Hyderabad, India, [email protected] \nDr. Nuray Ari, Ankara University, Turkiye, [email protected] \nDr. A.A. Mgbahurike, University of Port Harcourt, Nigeria, [email protected] \nSimilar Articles: \nKNOWLEDGE AND PERCEPTION OF MOLAR INCISOR HYPOMINERALIZATION AMONG DENTAL PRACTITIONERS IN SANA’A CITY- YEMEN \n\xa0PREVALENCE AND CAUSES OF TRAUMATIC DENTAL INJURIES TO ANTERIOR TEETH AMONG PRIMARY SCHOOL CHILDREN IN SANA A CITY, YEMEN