Radiological outcome of PLF surgeries in lumbar spine using DBM

Abstract

Introduction: Spinal fusion has become one of the most popular methods of treating spinal diseases such as trauma, deformity and degenerative disc disease. Ideally, in order to promote fusion, the bone graft or bone substitute should have both osteoinductive and osteoconductive properties. The demineralized bone matrix (DBM) of demineralized allosteric bone is processed by comprehensive decalcification procedures. These procedures include chemical and radiological steps to reduce the immune response and the risk of infection. The bone inductive activity of demineralized bone matrix (DBM) has been well demonstrated. DBM also appears to support new bone formation through bone conduction mechanisms. Case reports and analyzes of several retrospective non-randomized clinical series indicate that DBM in combination with autologous marrow or bone marrow demonstrate similar performance characteristics to autograft in posterior lumbar spinal fusion. The purpose of this study is to access radiological outcomes of PLF in lumbar spine using demineralized bone matrix (DBM).Purpose: To see Radiological Outcome of PLF (posteriolateral Fusion) Surgeries In Lumbar Spine Using Demineralized Bone Matrix (DBM).Methods: 30 patients were included in the study Patients were followed up postoperatively at one year follow up. The participants were evaluated for Radiological Outcome in the study group was assessed by using Lenke Classification of Posterolateral Fusion Surgeries In Lumbar Spine Using Demineralized Bone Matrix (DBM).Results: All patients followed up for one year. Radiological evaluation of Lumbar fusion rates assessed with Lenke fusion Classification for PLF at the end of one year was 83.33% Grade. A fusion rates which is excellent. Younger patients of either sex had better outcomes compared to the older age group patients.Conclusions: The average improvement across the board was 81.40% which is excellent. The available literature shows similar results compared to an iliac bone graft which is the gold standard for spinal fusion. DBM can be considered a reliable alternative to the autograft when used as a graft expander in combination with the autograft.