Случай острого В-лимфобластного лейкоза у ВИЧ-инфицированного пациента с хроническим вирусным гепатитом С

Abstract

Purpose . To observe clinical course of acute B cell lymphoblastic leukaemia and HIV infection combination from the point of view of current treatment conceptions for thus patients. Materials and methods . A clinical case of acute B cell lymphoblastic leukaemia in HIV-infected patient is presented. Results and discussion . 39-year old HIV-infected male with acute B cell lymphoblastic leukaemia received chemotherapy with the ALL-2009 regimen simultaneously with anti-retroviral therapy accompanied by severe leukopenia complicated with pneumonia by the force of strong comorbidity resulting to lethal outcome. Summary . Nowadays acute B cell lymphoblastic leukaemia and HIV infection combination that predestine poor prognosis in the accordance of special infection and immune status within the comorbidity of the patients, what demands to establish particular guidelines for chemotherapy, target therapy, maintenance treatment and bone marrow stem cell transplantation to improve efficiency of therapeutic influence at the course of heamoblastosis, so as HIV infection.