Hypercalcaemia in an idiopathic hypoparathyroidism patient, due to sarcoidosis

Abstract

Idiopathic primary hypoparathyroidism is an infrequent disease among adults, especially if not associated with genetic disease such as Di George syndrome. Most commonly hypoparathyroidism is a result of surgical removal of the parathyroid glands during operation in the cervical area. Sarcoidosis is a multiorgan granulomatous disease, more frequently encountered than primary hypothyroidism. Hypocalcaemia is the most common finding in hypoparathyroidism. The opposite characterizes, hypercalcaemia is finding, in some cases of sarcoidosis due to 1.25(OH) 2 D 3 from granulomas. Concomitant idiopathic hypoparathyroidism and sarcoidosis has rarely been described. Here, we describe a rare case of an elderly woman with idiopathic primary hypoparathyroidism who developed hypercalcaemia attributed to underlying sarcoidosis.