Archive | 2021
MULTI-DIMENSIONAL EVALUATION OF THE PRESENCE OF SARCOPENIA IN PATIENTS WITH KNEE OSTEOARTHRITIS
Abstract
Aim: In this study, we evaluated the presence of sarcopenia\nmultidimensionally in patients with knee osteoarthritis (OA) using\nclinical, ultrasonographic and biochemical parameters, and in this\nrespect, it was aimed to investigate the relation between OA and\nsarcopenia and to identify the most practical, easily accessible and\ninexpensive method for investigating sarcopenia.Materials and methods:\n102 patients with clinical and radiological diagnosis of knee\nosteoarthritis and 33 healthy control subjects were included in the\nstudy. The detailed musculoskeletal system examination of the patients\nincluded in the study was carried out by a single physician, and blood\nsample tests were recorded .Dual-X-ray absorptiometry (DEXA) is used to\nmeasure Body composition parameters and muscle mass measurements,\nisometric muscle strength evaluations, handgrip strength and gait speeds\nfor diagnosis of sarcopenia. Short-form -36 (SF-36) The Nutritional\nAssessment-short form (MNA), the Western Ontario and McMaster\nUniversities Osteoarthritis Index (WOMAC), the International Physical\nAssessment Questionnaire Short Form (IPAQ-SF) and the Center for\nEpidemiologic Studies Depression Scale (CES-D scale) were administered\nto every patient as outcome measures.Results: Body composition parameter\nresults showed that sarcopenic patients had statistically lower values\nas fat mass, lean body mass and skeletal muscle index (p\n<0.001, p= 0.001, p <0.001, respectively) than those\nof non-sarcopenic and control group. It was determined that body\ncomposition values measured with DEXA, ultrasonographic measures,\nisokinetic muscle strength assessment, handgrip strength and gait speed\nhad predictive values for sarcopenia. Conclusion: We found that patients\nwith sarcopenic OA were older, weaker, undernourished, and restricted in\ntheir level of physical activity in the study in which we identified\nsarcopenia as approximately 12% in patients with osteoarthritis. Among\nthe methods of determining sarcopenia, ultrasound becomes prominent with\nits practical, cheap and easily accessible features. We think that our\nresults will increase the awareness of the presence of sarcopenia in OA\npatients.