Postoperative Bronchospasm in a Child with Coffin-Siris Syndrome Following Administration of Sugammadex

Abstract

A 13-year-old boy with Coffin-Siris syndrome was scheduled to undergo dental surgery for dental treatment with general anesthesia. Mental retardation, finger anomalies and coarse facies features were recorded in preoperative assessment. Propofol, Fentanyl and Rocuronium were given for anesthesia induction. Sevoflurane was used as an inhalation anesthetic drug in anesthesia maintenance. At the end of the operation, the patient was extubated using sugammadex as a neuromuscular reversal drug. After the extubation, bronchospasm appeared. The patient treated for bronchospasm. At the postoperative care unit, the patient’s vital signs were followed for a while and discharged on postoperative day without any problems. For the reason those pulmonary problems of the patients with Coffin-Siris syndrome which was unknown or underestimated before anesthesia, sugammadex administration is a risk for bronchospasm. Consequently, pre-anesthetic evaluation should be performed carefully in patients with Coffin-Siris syndrome to be treated with sugammadex and notely respiratory pathologies should be questioned.