Rheumatology and Immunology Research | 2021

The role of 14-3-3 η as a biomarker in rheumatoid arthritis

 
 
 

Abstract


Abstract Rheumatoid arthritis (RA) is a chronic multisystem inflammatory disorder with significant morbidity and mortality. Making an early diagnosis and providing appropriate treatment decisions based on clinical and other parameter results in good disease control. Biomarkers, such as C reactive protein (CRP), anti-cyclic citrullinated peptides (anti-CCP), and erythrocyte sedimentation rate (ESR), have been traditionally used. Recently novel biomarkers are described. This article reviews the evidence behind a novel biomarker 14-3-3 η that has been found to provide additional diagnostic and prognostic information as well as predicting response to treatment. A systematic literature review is presented showing the evidence behind this molecule.

Volume 2
Pages 87 - 90
DOI 10.2478/rir-2021-0012
Language English
Journal Rheumatology and Immunology Research

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