A New Azo Dye for the Selective Detection of Glycine

Abstract

In this manuscript, we report the synthesis of new azo\ndye (E)-4-((5-methoxythiazolo[4,5-b]pyridine-2-yl)diazenyl)N-phenylaniline (BK2).\nThis new azo dye revealed a pink color in the solution. Notably, this dye\nselectively detects only glycine among all the amino acids and a visual color\nchange from light pink to purple can be assessed. Hence, the new azo dye finds application as colorimetric\nchemosensor for the rapid, selective and sensitive detection of glycine (Gly). The\ndye can be potentially used for the detection of high levels of glycine in the\nserum caused due to hyperglycinaemia.