Therapeutic Use of Convalescent Plasma in COVID-19 Infected Patients with Concomitant Hematological Disorders

Abstract

Passive immunotherapy with plasma collected from patients recovered from SARS-CoV-2, known as convalescent plasma (CP), is a promising option for the treatment of COVID-19-infected patients. The transfusion of convalescent blood products with the goal of providing passive immunity has been in use for at least a century to treat a number of diseases ranging from polio, chickenpox, and measles, to SARS and Middle East respiratory syndrome (MERS). More recently, the WHO proposed the use of CP as an early treatment for patients affected with Ebola virus disease [3,4].