Adaptation to the levels of MDA and SOD Enzyme Activity of MICT and HIIT Exercise On Wistar

Abstract

The purpose of this study is to reveal the influence of moderate intensity continuous training (MICT) and highintensity interval training (HIIT) against the levels of malondialdehyde (MDA) and superoxide dismutase enzyme activity (SOD) in blood circulation. The sample in this study used 21 male Wistar rat tail based on criteria for inclusion and was divided into three treatment groups (control, MICT, HIIT). MICT method applied with exercise intensity 60-80% baseline maximum ability, whereas the method of exercise HIIT applied with 100% intensity baseline maximum ability. Exercise interventions in this study provided for 6 weeks with a frequency of four times per week. MDA levels have known data collection based on the reading of the spectrophotometry of blood serum. SOD enzyme activity is known by observation rate of inhibition of the reduction of ferisitokrom c by superoxide anion from xanthine/xanthine oxidase. The results showed that exercise HIIT and influence the MICT method changes the levels of MDA (Sig. < 0.05), but no effect on enzyme activity of SOD (Sig. > 0.05). It shows, MICT method considered more safe and effective in improving metabolic status based on the trend of changes in average levels of MDA and SOD enzyme activity. key words—MDA, SOD, MICT, HIIT.